The Peptide Desalting Products from MtoZ Biolabs provide clean, reliable peptide samples for LC-MS/MS preparation by enabling efficient removal of post-digestion contaminants. Following enzymatic digestion, residual salts, detergents, buffer components, and other low-molecular-weight impurities can significantly compromise ionization efficiency and overall data quality in mass spectrometry. The Classical Peptide Desalting platform is engineered for rapid and thorough cleanup of these interfering substances, offering multiple consumable formats, including peptide desalting plates, C18 rapid desalting pipette tips, and C18 peptide desalting spin columns, to support diverse sample volumes, throughput requirements, and automation workflows. High-purity peptide samples can be obtained within minutes, establishing a robust foundation for downstream LC-MS/MS analysis.
Advantages
1. Multiple Formats for Flexible Workflow Integration
The Peptide Desalting Products from MtoZ Biolabs are offered in multiple consumable formats, including 96-well desalting plates, single-sample spin columns, and desalting pipette tips compatible with standard pipettors, supporting scenarios from single-sample cleanup to high-throughput automated purification.
2. Superior Desalting and Cleanup Performance
High-capacity, high-selectivity C18 or mixed-mode reversed-phase media efficiently retain peptides while removing salts, SDS, urea, glycerol, and other common contaminants, ensuring clean mass spectrometric backgrounds.
3. High Recovery and Excellent Reproducibility
MtoZ Biolabs' Optimized sorbent materials and column geometries enable consistent high recovery even for low-input (down to microgram-scale) or hydrophobic peptides. Standardized operating workflows promote robust batch-to-batch reproducibility in proteomic sample preparation.
4. Simple and Rapid Operation
Most devices are supplied ready-to-use and require no special instrumentation or activation steps. Typical workflows involve only loading, washing, and elution, allowing single-sample or batch purification to be completed within minutes and greatly improving pre-LC-MS preparation efficiency.
5. Broad Mass Spectrometry Compatibility
Washing and elution are performed using MS-compatible solvents (e.g., water/acetonitrile with formic acid), enabling direct LC-MS injection or vacuum concentration without secondary processing steps that increase sample loss.
Technical Support
1. Protocol Downloads
MtoZ Biolabs provides comprehensive experimental protocols and product manuals to help ensure smooth and reproducible workflows. For access to specific documents or detailed instructions, please contact our support team.
2. Customized Service Support
Our experienced scientists offer tailored technical assistance and customized solutions based on your specific research goals, helping you achieve optimal experimental outcomes.
3. FAQ and Expert Assistance
We provide responsive and professional technical support to address your questions efficiently. Our experts are ready to help you identify and resolve experimental challenges quickly and accurately.
- SPE C18 Desalting ColumnQuantity: 5 Columns
- STip C18 Rapid Peptide Desalting TipQuantity: 50 tips
- C18 Peptide Desalting Spin ColumnQuantity: 5 Columns
- Peptide Desalting PlateQuantity: 1 plate
- Stage-tip Desalting KitQuantity: 50 reactions
- SP2 Magnetic Beads Based Peptide Desalting KitQuantity: 50 reactions
