EASY-Spray HPLC Column from MtoZ Biolabs is an integrated nanoLC separation and emitter chromatography column designed to deliver stable spray and reproducible peptide separations for LC-MS based proteomics.
Product Overview
Routine nanoLC-MS can be difficult to scale and standardize because small changes at the column and emitter interface can quickly turn into run-to-run variability, including the following common failure modes and sources of performance drift.
1. Emitter Instability
Traditional tips and uneven spray behavior can cause signal drift, intermittent spray, and missing identifications.
2. Connection Variability
Extra fittings and dead volume at junctions can broaden peaks and reduce separation efficiency.
3. Clogging and Fragility
Narrow flow paths are prone to blockage and breakage, especially with complex matrices or repeated injections.
4. Reproducibility Gaps
Column to column differences and inconsistent setup can complicate method transfer and long series studies.
Advantages
✅ Integrated Spray Design
A built-in emitter supports a steady electrospray and reduces the setup variables that drive LC-MS variability.
✅ Zero-Dead-Volume Connection
An innovative fitting creates a true zero-dead-volume junction, helping preserve narrow peaks and maintain chromatographic resolution.
✅ Reproducible Performance
MtoZ Biolabs EASY-Spray HPLC Column is designed for consistent retention and spray behavior across runs and columns.
✅ Proteomics Ready Robustness
Improved tolerance to routine handling and complex peptide samples helps reduce clogs and downtime in everyday workflows.
Technical Support
1. Protocol Downloads
MtoZ Biolabs provides comprehensive experimental protocols and product manuals to help ensure smooth and reproducible workflows. For access to specific documents or detailed instructions, please contact our support team.
2. Customized Service Support
Our experienced scientists offer tailored technical assistance and customized solutions based on your specific research goals, helping you achieve optimal experimental outcomes.
3. FAQ and Expert Assistance
We provide responsive and professional technical support to address your questions efficiently. Our experts are ready to help you identify and resolve experimental challenges quickly and accurately.







