MtoZ Biolabs 0.1% Formic Acid (v/v), LC-MS Grade is a premixed mobile-phase additive for high-sensitivity LC-MS analysis. It enables consistent LC-MS/UHPLC-MS mobile-phase acidification and enhanced ionization, improving peptide and protein peak shape, separation performance, and signal-to-noise ratio. This formulation is widely used for proteomics identification and quantification as well as method development.
Product Overview
In trace-level protein and peptide analysis, even minor differences in mobile-phase composition can be amplified into major performance issues:
1. Peak Tailing
Peptides can undergo nonspecific adsorption to residual silanol groups on the LC column, leading to broader peaks and reduced resolution.
2. Sensitivity Bottlenecks
Mobile-phase impurities may cause ion suppression and mask low-abundance protein signals, increasing the risk of missed detections.
3. Poor Reproducibility
Manual preparation can introduce environmental contamination and concentration variability, resulting in retention time drift and compromising consistency in large-cohort studies.
Advantages
✅ Validated
Compatible with mainstream LC-MS workflows and common reversed-phase conditions, supporting routine proteomics runs and method evaluation while improving data reproducibility and cross-batch consistency.
✅ Purified
Tightly controlled metal ions (<50 ppb) and organic impurities to minimize ghost peaks and metal-adduct interference, delivering an exceptionally clean background.
✅ Convenient
A ready-to-use 0.1% (v/v) formulation that reduces weighing errors and contamination risks associated with in-house preparation, improves efficiency, and fits high-throughput and standardized workflows.
Technical Support
1. Protocol Downloads
MtoZ Biolabs provides comprehensive experimental protocols and product manuals to help ensure smooth and reproducible workflows. For access to specific documents or detailed instructions, please contact our support team.
2. Customized Service Support
Our experienced scientists offer tailored technical assistance and customized solutions based on your specific research goals, helping you achieve optimal experimental outcomes.
3. FAQ and Expert Assistance
We provide responsive and professional technical support to address your questions efficiently. Our experts are ready to help you identify and resolve experimental challenges quickly and accurately.
