IP-MS Validated Tag Antibodies for IP, Co-IP, and IP-MS Workflows

Tag antibodies are widely used for the detection, enrichment, purification, and localization of recombinant proteins carrying common epitope or fusion tags. MtoZ Biolabs provides antibodies against widely used tags such as FLAG, HA, Myc, His, GST, and GFP, supporting routine applications including Western blotting, immunoprecipitation, co-immunoprecipitation, immunofluorescence, and affinity-based protein enrichment.

For studies extending from tagged protein enrichment to protein complex and interaction analysis, MtoZ Biolabs also provides integrated protein interaction mass spectrometry services, including IP-MS and Co-IP-MS, to support the identification and characterization of protein-associated complexes and interaction partners.

IP-MS Validated Tag Antibodies for IP, Co-IP, and IP-MS Workflows

Tag Antibodies for Recombinant Protein Detection and Enrichment

MtoZ Biolabs offers tag antibodies for the detection, enrichment, purification, and localization of tagged recombinant proteins, with options suitable for WB, IP, Co-IP, IF, affinity enrichment, and downstream IP-MS workflows.

Our portfolio includes IP-MS validated antibodies against commonly used epitope, affinity, and fluorescent tags, including DYKDDDDK (FLAG), HA, Myc, His/6x-His, GFP/EGFP, GST, MBP, SUMO, V5, mCherry, Strep Tag II, and more. Available formats include monoclonal, polyclonal, and recombinant monoclonal antibodies, with product options varying by tag.

Protein Detection

Detection and localization of tagged recombinant proteins by Western blotting, immunofluorescence, and other supported applications.

IP and Co-IP

Immunoprecipitation of tagged bait proteins and co-enrichment of associated protein complexes.

Affinity Enrichment

Tag-specific capture and enrichment of recombinant proteins for purification or downstream analysis.

IP-MS and Co-IP-MS

Enrichment of tagged proteins or protein complexes followed by LC-MS/MS-based identification and interaction analysis.

Common Tag Antibody Options
DYKDDDDK / FLAG
Antibodies for FLAG/DYKDDDDK-tagged proteins, with monoclonal and recombinant monoclonal options available.
His / 6x-His
Antibodies for His-tagged recombinant proteins, including 6x-His and recombinant antibody options.
GFP / EGFP
Antibodies for GFP-, EGFP-, and related fluorescent fusion proteins.
HA / Myc
Common epitope tag antibodies for recombinant protein detection, enrichment, and interaction studies.
Additional Tags
GST, MBP, SUMO, V5, mCherry, Strep Tag II, multi-tag antibodies, and more.

Where Tag Antibodies Are Used

Tag antibodies support recombinant protein detection, enrichment, localization, and interaction analysis across a broad range of biological research.

Cancer Research

Study tagged oncogenes, tumor suppressors, signaling proteins, and protein complexes in cancer cell models, including expression, localization, enrichment, and interaction analysis.

Cell Signaling

Track and enrich tagged receptors, kinases, adaptor proteins, and pathway components to examine signaling complexes and pathway-associated protein interactions.

Neuroscience

Support studies of tagged receptors, ion channels, transporters, synaptic proteins, and other neuronal proteins in expression, localization, and complex analysis.

Immunology

Analyze tagged immune receptors, signaling molecules, and regulatory proteins in immune-cell pathways, protein enrichment, and interaction studies.

Infectious Disease Research

Investigate tagged viral, bacterial, and host proteins in pathogen protein expression, localization, enrichment, and host–pathogen interaction studies.

From Tag-Based Enrichment to Protein Interaction Mass Spectrometry

For projects that continue beyond antibody selection, MtoZ Biolabs provides downstream IP-MS, Co-IP-MS, and affinity purification-mass spectrometry services for tagged bait and protein complex studies.

Frequently Asked Questions

Key considerations for tag antibody selection, immunoprecipitation, and downstream mass spectrometry workflows.

Q1How should I select a tag antibody for my recombinant construct?

Q2Are these tag antibodies suitable for IP and downstream mass spectrometry?

Q3Can the same tag antibody be used for both Western blotting and immunoprecipitation?

Q4Does N-terminal or C-terminal tag placement affect immunoprecipitation?

Q5How do I choose between monoclonal, recombinant monoclonal, and polyclonal tag antibodies?

Q6Can MtoZ Biolabs support IP-MS or Co-IP-MS after antibody selection?

Find the Right Antibody for Your Research

Selecting the right antibody depends on target specificity, sample species, antibody format, host species, application, validation method, and downstream experimental goals. Use our product filter to quickly identify antibody products that match your experimental requirements.

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