Target-Specific Recognition
Directly target endogenous proteins of interest without introducing an affinity tag, supporting native protein studies in biologically relevant systems.
Target protein antibodies enable direct detection and enrichment of specific endogenous proteins and native protein complexes without introducing an affinity tag. MtoZ Biolabs provides IP-MS validated antibodies against a broad range of protein targets, supporting applications such as Western blotting, immunoprecipitation, co-immunoprecipitation, immunofluorescence, and protein interaction studies.
For studies extending from target enrichment to protein complex and interaction analysis, MtoZ Biolabs also provides downstream protein interaction mass spectrometry services, including IP-MS and Co-IP-MS, to support the identification and characterization of target-associated proteins and native protein complexes.

MtoZ Biolabs offers IP-MS validated antibodies against a broad range of endogenous protein targets, with product options for detection, immunoprecipitation, co-immunoprecipitation, and downstream protein interaction mass spectrometry workflows. Our target protein antibody portfolio covers signaling molecules, receptors, transcriptional regulators, metabolic enzymes, cytoskeletal proteins, immune-related proteins, and more. Available formats include polyclonal, monoclonal, and recombinant monoclonal antibodies, with product options varying by target.
Directly target endogenous proteins of interest without introducing an affinity tag, supporting native protein studies in biologically relevant systems.
Support immunoprecipitation-based enrichment of endogenous proteins together with associated protein complexes under native or near-native conditions.
Compatible with multiple downstream applications, including target confirmation, co-immunoprecipitation, protein complex analysis, and interaction studies.
Suitable for enrichment workflows that continue to LC-MS/MS, supporting interacting protein identification and protein complex characterization.
Selected products from the MtoZ target protein antibody portfolio. Product availability and supported applications vary by target and antibody format.
The MtoZ target protein antibody portfolio supports endogenous protein detection, immunoprecipitation, complex enrichment, and interaction analysis across major areas of molecular and cellular research.
Study growth factor receptors, oncogenic kinases, tumor suppressors, immune checkpoints, and cancer-associated complexes, including targets such as EGFR, HER2/ErbB2, KRAS, BRAF, p53, and PD-L1/CD274.
Investigate endogenous receptors, kinases, transcriptional regulators, and pathway components involved in AKT, ERK/MAPK, JAK/STAT, NF-κB, mTOR, and related signaling networks.
Analyze immune receptors, CD markers, Toll-like receptors, cytokine-associated proteins, checkpoint molecules, and inflammatory signaling complexes in immune-cell systems.
Examine caspases, BCL-2 family proteins, PARP, cyclins, CDKs, LC3B, ATG proteins, SQSTM1/p62, and related regulators of cell death, proliferation, and proteostasis.
Study metabolic enzymes and mitochondrial proteins involved in energy metabolism, lipid metabolism, redox regulation, and respiratory processes, including ACLY, ALDH, AMPK, ATP synthase, NDUF, and IDH-related targets.
Support endogenous protein studies involving neuronal markers, synaptic proteins, receptors, transporters, and neurodegeneration-associated targets such as GFAP, NeuN, MAP2, PSD95, Tau, APP, and NMDAR proteins.
For projects extending beyond antibody selection, MtoZ Biolabs provides downstream and complementary protein interaction mass spectrometry services for endogenous target proteins, native protein complexes, and interaction systems requiring alternative enrichment strategies.
Key considerations for target protein antibody selection, immunoprecipitation, and downstream mass spectrometry workflows.
Selecting the right antibody depends on target specificity, sample species, antibody format, host species, application, validation method, and downstream experimental goals. Use our product filter to quickly identify antibody products that match your experimental requirements.
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