The MtoZ Biolabs' Dialysis Cassettes feature a revolutionary flat cassette architecture that enables knot-free, tool-free, and highly efficient dialysis with exceptional sample recovery.
Product Overview
Conventional dialysis approaches rely on cylindrical dialysis tubing, which introduces multiple operational bottlenecks and compromises both efficiency and sample yield:
1. Complex and Error-Prone Handling
Traditional dialysis tubing requires clamps, knots, or sealing devices. These steps are laborious and prone to user-dependent variation, increasing the likelihood of leakage, sample loss, and workflow interruptions, particularly when processing small or multiple samples simultaneously.
2. Low Dialysis Efficiency
Cylindrical tubing exhibits a low surface area-to-volume ratio, resulting in slow diffusion kinetics during buffer exchange or desalting. Dialysis often requires overnight processing or longer, delaying downstream workflows.
3. Poor Sample Recovery
Recovering viscous or low-volume samples from narrow tubing is difficult and frequently incomplete, leading to loss of valuable protein material and compromising downstream quantitative accuracy.
4. Non-Intuitive Sizing and Labeling
Dialysis tubing formats are difficult to select and lack clear differentiation of MWCO specifications, increasing the risk of using incorrect cutoff membranes during sample preparation.
Advantages
✅ Unprecedented Ease of Operation
The MtoZ Biolabs' Dialysis Cassettes adopt an innovative flat cassette design with a self-sealing injection port. Samples can be loaded and retrieved directly using a syringe or pipette, no knots, no clamps, and no sealing caps required. This streamlined design eliminates leakage concerns and dramatically simplifies handling.
✅ Exceptionally High Dialysis Efficiency
A dual-membrane flat chamber maximizes the membrane surface area relative to sample volume, accelerating diffusion of small molecules and significantly reducing dialysis time. Compared to conventional dialysis tubing, processing can be shortened by several hours, enabling faster experimental turnaround.
✅ Near-Quantitative Sample Recovery
The rectangular geometry and corner-based access ports enable nearly 100% sample recovery using either syringe aspiration or pipetting. Even viscous or low-volume specimens can be recovered completely, preserving precious biomaterials for proteomics, structural biology, and enzymology applications.
✅ Flexible Specification Options
Multiple cassette formats and MWCO options are available to accommodate applications ranging from micro-scale precious samples to preparative-scale protein purification.
✅ High-Purity, Low-Binding Materials
The dialysis membrane is composed of low-binding regenerated cellulose with minimal extractables. Membranes contain trace glycerol (21%) to maintain flexibility and exhibit extremely low sulfur and heavy metal content. Sterile, γ-irradiated packaging is available to minimize contamination risk for sensitive downstream assays.
Technical Support
1. Protocol Downloads
MtoZ Biolabs provides comprehensive experimental protocols and product manuals to help ensure smooth and reproducible workflows. For access to specific documents or detailed instructions, please contact our support team.
2. Customized Service Support
Our experienced scientists offer tailored technical assistance and customized solutions based on your specific research goals, helping you achieve optimal experimental outcomes.
3. FAQ and Expert Assistance
We provide responsive and professional technical support to address your questions efficiently. Our experts are ready to help you identify and resolve experimental challenges quickly and accurately.
