Resources
Proteomics Databases
Metabolomics Databases
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10x multiome sequencing is a cutting-edge, high-throughput single-cell technology developed on the 10x Genomics platform. It enables the simultaneous profiling of multiple omics layers—such as transcriptomics, epigenomics, TCR/BCR sequences, cell surface protein expression, and spatial localization—at the single-cell or even subcellular level. Initially derived from in-depth studies of single-cell transcriptomics, this technology has evolved in response to increasing recognition of the complexity of c......
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Microbiome proteomics aims to comprehensively characterize the protein composition and functional dynamics of complex microbial communities. The microbiome refers to the collective population of microorganisms—including bacteria, fungi, and viruses—inhabiting a specific environment. These microbial communities engage in intricate interactions with their hosts, significantly influencing host health, ecosystem balance, and biogeochemical cycles. Through microbiome proteomics, scientists can gain in-de......
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• Single Nuclei Sequencing 10x
Single nuclei sequencing 10x enables high-resolution genomic analysis at the level of individual cells. This technology allows researchers to obtain gene expression profiles from single cells, providing deep insights into complex biological systems. Its application spans a broad range of biomedical research fields, including cancer research, neuroscience, and immunology. In cancer research, single nuclei sequencing 10x allows for the dissection of intratumoral heterogeneity by identifying gene expre......
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• In Silico Analysis of Protein-Protein Interaction
In silico analysis of protein-protein interaction is a scientific approach that utilizes computational technologies and bioinformatics tools to predict and investigate interactions between proteins. As central executors of various biological processes within cells, proteins form complex networks through their interactions to carry out diverse biological functions. Understanding these interactions is critical for uncovering the mechanisms of biological processes, identifying the molecular basis of dise......
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• 10x Genomics Whole Genome Sequencing
10x Genomics whole genome sequencing is an advanced molecular biology technique designed to analyze the complete genome of an organism. It plays a vital role in molecular biology research by providing detailed information on genomic structure, function, and genetic variation. In basic research, 10x Genomics whole genome sequencing enables scientists to decipher genome architecture, explore gene functions, and identify interactions among genes. For example, by analyzing genomic variants and regulatory ......
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• 10x Single Cell DNA Sequencing
10x single cell DNA sequencing enables high-resolution genomic analysis at the single-cell level. This technology allows researchers to identify and examine the genomic characteristics of individual cells within complex tissues or heterogeneous cell populations, overcoming the limitations of population-averaged data. Its core strength lies in enabling scientists to track genetic alterations in single cells, uncover variations among different cell types, and identify critical genetic markers associated......
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• 10x Genomics V(D)J Sequencing
10x Genomics V(D)J sequencing is a single-cell sequencing technology primarily designed for detailed analysis of T cell and B cell receptors in the immune system. By capturing and sequencing V(D)J recombination sequences from individual cells, this technology enables researchers to explore immune cell diversity and specificity, thereby offering a powerful tool to gain deep insights into immune system mechanisms. It plays a crucial role in fields such as cancer immunotherapy, autoimmune disease researc......
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• Cancer Genomics and Proteomics
Cancer genomics and proteomics are two foundational disciplines for exploring the molecular mechanisms of cancer. They respectively reveal the nature and evolution of tumors from the perspectives of genetic information and protein function. Cancer genomics focuses on alterations at the DNA level in cancer cells, including gene mutations, copy number variations, chromosomal rearrangements, and epigenetic modifications, all of which constitute the genetic basis of tumorigenesis. In contrast, cancer prot......
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• Photoaffinity Labeling in Target and Binding Site Identification
Photoaffinity labeling in target and binding site identification represents an advanced approach at the interface of chemistry and biotechnology. It is designed to accurately elucidate the interactions between small molecules and their protein targets, with a particular focus on the spatial localization and binding mechanisms of interaction sites. In contemporary drug discovery and molecular mechanism studies, understanding where and how small molecules engage with target proteins underpins the .........
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GTEx (Genotype-Tissue Expression) Proteomics represents a systematic research initiative that extends the scope of the original GTEx project. It aims to construct a comprehensive landscape of protein expression across diverse human tissues and to further investigate how genetic variation influences the spatial distribution and functional modulation of proteins. While the initial GTEx project primarily focused on uncovering inter-individual variability and tissue specificity in gene expression using ........
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